Yes, it is a Bugs Bunny and Marvin the Martian in the cartoon known as Hasty Hare. Just watch it before you read any more. OK?
About 5:40 the cartoon really takes off as far as I am concerned. Bugs drops anchor from the spaceship and all sorts of mayhem ensues.
You wont see the "Palomar" reference until a little later (6:19) as an observatory comes into view. The observatory looks a lot like Mt. Wilson. Wouldn't you agree?
Here's the cartoon version:
And the real thing:
That's much more than a passing resemblance. It looks to me like the artist used Mt. Wilson as the subject for the cartoon.
Finally, here's the observatory with the various astronomical objects that Bugs has managed to drag along.
The Palomar reference (and the admittedly weak Thanksgiving reference, well it is more to do with turkeys) comes at the end when the observatory's director, I.
Yes, it is the Shalomar Observatory. The cartoon was released in 1951 just a few years after the Hale Telescope at Palomar became the world's largest telescope.
As far as I know no employee of the Palomar Observatory has ever resigned to take up turkey farming - yet.
UPDATE: Commenter Anonymous points out that it was actually I. Frisby who signed the letter (I must need to get my glasses checked) and that the astronomer is a caricature of Warner Brothers animator Fritz Freleng.
Judging by the number of comments & emails I have received on this post I would say that I need to have more cartoon astronomy posts in the future.