Yes, it is a Bugs Bunny and Marvin the Martian in the cartoon known as Hasty Hare. Just watch it before you read any more. OK?
About 5:40 the cartoon really takes off as far as I am concerned. Bugs drops anchor from the spaceship and all sorts of mayhem ensues.
You wont see the "Palomar" reference until a little later (6:19) as an observatory comes into view. The observatory looks a lot like Mt. Wilson. Wouldn't you agree?
Here's the cartoon version:


Finally, here's the observatory with the various astronomical objects that Bugs has managed to drag along.


As far as I know no employee of the Palomar Observatory has ever resigned to take up turkey farming - yet.
UPDATE: Commenter Anonymous points out that it was actually I. Frisby who signed the letter (I must need to get my glasses checked) and that the astronomer is a caricature of Warner Brothers animator Fritz Freleng.
Judging by the number of comments & emails I have received on this post I would say that I need to have more cartoon astronomy posts in the future.